Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1989-01-23
1991-12-17
Russel, Jeffrey E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
530345, 530363, 530380, 530386, 530395, 530403, 530404, 530406, 530408, 530409, 436536, 436546, C07K 1702, C07K 1514, G01N 33536
Patent
active
050736299
ABSTRACT:
A fluorescence polarization immunoassay for detecting the presence of methadone in a test sample is provided, based upon competition between methadone and a fluorescently labeled tracer for the binding sites on an antibody specific for methadone. The concentration of methadone in the sample determines the amount of tracer that binds to the antibody. The amount of tracer-antibody complex formed can be quantitatively measured and is inversely proportional to the quantity of methadone in the sample. Tracers used as reagents and immunogens used to raise antibodies for use as reagents are also disclosed.
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Dubler Robert E.
Thacker Susan A.
Walling John A.
Wang Nai-Yi
Abbott Laboratories
Breininger Thomas M.
Hastreiter Roberta
Kim Kay
McNeil James D.
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