Metered electro-dose

Surgery – Respiratory method or device – Means for mixing treating agent with respiratory gas

Reexamination Certificate

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C128S203120, C424S489000

Reexamination Certificate

active

06868853

ABSTRACT:
An electro-dose constitutes a metered medical powder and is formed from an electro-powder constituting an active powder substance or a dry powder medical formulation being transferred onto a device member forming a dose carrier. The electro-dose prepared from an electro-powder presents a fine particle fraction (FPF) having of the order 50% or more of its content with a particle size between 0.5-5 μm. The electro-powder of such a metered electro-dose further provides electrostatic properties regarding absolute specific charge per mass after charging of the order 0.1 to 25 μC/g and presents a charge decay rate constant Q50of more than 0.1 sec with a tap density of less than 0.8 g/ml and a water activity awof less than 0.5. The electro-dose porosity is adjusted to obtain an optimized porosity value in percent of 75 to 99.9 calculated as 100−100×(Densityelectro-dose/Densityelectro-powder).

REFERENCES:
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patent: 6007630 (1999-12-01), Pletcher et al.
patent: 6063194 (2000-05-01), Poliniak et al.
patent: 6565885 (2003-05-01), Tarara et al.
patent: 6638495 (2003-10-01), Weers et al.
patent: 9700704 (1997-01-01), None
patent: 9832479 (1998-07-01), None
patent: WO 9832479 (1998-07-01), None
patent: 0006235 (2000-02-01), None
patent: 0006236 (2000-02-01), None

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