Metered dose inhaler fomulations which include the ozone-friendl

Details Metered dose inhaler fomulations which include the ozone-friendl Metered dose inhaler fomulations which include the ozone-friendl

1994-03-23

1996-02-20

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424 46, 252305, 514958, A61K 912

Patent

active

054926882

ABSTRACT:
Metered dose inhaler (MDI) formulations which utilize 1,1,1,2-tetrafluoroethane (HFC 134a) as the sole propellant are made practical by including a polar surfactant such as polyethylene glycol, diethylene glycol monoethyl ether, polyoxyethylene (20) sorbitan monolaurate, polyoxyethylene (20) sorbitan monooleate, propoxylated polyethylene glycol, and polyoxyethylene (4) lauryl ether for suspending, solubilizing, wetting and emulsifying the drug constituent and lubricating the valve components of the MDI.

REFERENCES:
patent: 4174295 (1979-11-01), Bargigia et al.
patent: 4945119 (1990-07-01), Smits et al.
patent: 5190029 (1993-03-01), Byron et al.
patent: 5202110 (1993-04-01), Dalby et al.

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