Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1996-11-15
1999-11-16
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
A61K 3119
Patent
active
059859245
ABSTRACT:
The present invention provides novel metastasis suppressory agents with a lowered degree of toxicity, comprising ursolic acid or its salt as an active ingredient, which can be administered to patients per os or through injection, thus enabling the patients to receive post-operative ambulatory treatment.
REFERENCES:
Cancer Letters, Vol. 94, No. 2, 1995, pp. 213-218, Kyung-Hee Sohn et al., "Anti-angiogenic activity of triterpene acids".
Br. J. of Cancer, Vol, 72, No. 2, Oct. 1995, pp. 257-267. CT Baillie et al., "Tumour vasculature --a potential therapeutic target".
Ann. N.Y. Acad. Science Vol. 732, Sep. 6, 1994, pp. 263-272, Eric P. Sipos et al., "Inhibition of Tumor Angiogenesis".
Hirota Mitsuru
Ishikawa Hiromichi
Nishimuro Satoshi
Watanabe Tomoko
Goldberg Jerome D.
JCR Pharmaceuticals Co. Ltd.
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