Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-03-25
1999-12-28
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548517, 5483147, 548156, 5462727, 5462764, 514336, 514340, 514343, 514427, A61K 3140, C07D40512
Patent
active
060082437
ABSTRACT:
The present invention is directed to compound of the formula I: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, X, Y, and ##STR2## are as defined herein. These compounds are useful for inhibiting the activity of a metalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds.
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Abreo Melwyn A.
Bender Steven L.
Castelhano Arlindo L.
Chen Jian Jeffrey
Chong Wesley K. M.
Agouron Pharmaceuticals , Inc.
Aulakh Charanjit S
Rotman Alan L.
Syntex (U.S.A.) Inc.
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