Metalloproteinase inhibitor

Details Metalloproteinase inhibitor Metalloproteinase inhibitor

2011-08-09

2011-08-09

Spector, Lorraine (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S001100, C514S021300, C514S021100, C435S069200, C435S069700, C530S324000, C530S400000, C530S407000, C530S350000

Reexamination Certificate

active

07994136

ABSTRACT:
A novel metalloproteinase inhibitor, analogs thereof, polynucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders caused by excessive amounts of metalloproteinase are also disclosed.

REFERENCES:
Docherty et al “Sequence of Human Tissue Inhibitor of Metalloproteinases and its Identity to Erythroid-Potentiating Activity” Nature v.318, 66-69 (Nov. 1985).
Murray et al “Purification and Partial Amino Acid Sequence of a Bovine Cartilage-Derived Collagenase Inhibitor” J. Biol. Chem. v.261 (9) pp. 4154-4159. (Mar. 1986).
Bethesda Research Laboratories 1985 Catalog. p. 62.

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