Metallocene-based phosphorus chiral phosphines

Details Metallocene-based phosphorus chiral phosphines Metallocene-based phosphorus chiral phosphines

2011-03-15

2011-03-15

Lee, Rip A. (Department: 1762)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

C556S138000, C556S140000, C556S136000, C556S022000, C556S021000, C556S020000, C556S019000, C556S018000, C556S013000

Reexamination Certificate

active

07906669

ABSTRACT:
The present invention concerns a metallocene-based phosphine ligand for use in enantioselective catalysis, the ligand having the Formula (I): Wherein M is a metal; Z is P or As; L is a suitable linker; R1is selected from alkyl, alkoxy, alkylamino, cycloalkyl, cycloalkoxy, cycloalkylamino carbocyclic aryl, substituted and unsubstituted carbocyclic aryloxy, heteroaryl, heteroaryloxy, carbocyclic arylamino and heteroarylamino; X* is selected from (II): Wherein R, R2and R3are independently selected from optionally substituted branched- and straight-chain alkyl, cycloalkyl, heterocycloalkyl, carbocyclic aryl, and heteroaryl.

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