Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing
Reexamination Certificate
2011-08-09
2011-08-09
Lee, Rip A. (Department: 1762)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heavy metal containing
C556S144000, C556S057000, C556S136000, C556S137000, C556S138000, C502S152000, C502S153000, C502S154000, C502S155000, C502S208000, C502S210000, C502S213000, C502S200000
Reexamination Certificate
active
07994355
ABSTRACT:
The present invention relates to metallocene-based phosphine ligands having chirality at phosphorus and at least one other element of chirality (planar chirality and/or chirality at carbon); and to the use of such ligands in asymmetric transformation reactions to generate high enantiomeric excesses of formed compounds. A method for the preparation of ligands according to the invention involving the conversion of the ortho-lithiated substituted metallocene to a phosphine chiral at phosphorus is also disclosed.
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CAPLUS Accession No. 118:191947 (Abstract only) Kim, et al. “Functionalized organometallic ligand. 1. Synthesis of some ferrocene derivatives of cyclohexyl- and cyclopentadienylphosphines” Bulletin of the Korean Chemical Society 1992, 13(6), 588-92.
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Chen Wei-Ping
Whittall John
Lee Rip A.
Solvias AG
Wenderoth , Lind & Ponack, L.L.P.
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