Metallization of nucleic acids via metal nanoparticles...

Details Metallization of nucleic acids via metal nanoparticles... Metallization of nucleic acids via metal nanoparticles...

2005-04-26

2005-04-26

Fredman, Jeffrey (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C514S04400A, C536S023100

Reexamination Certificate

active

06884587

ABSTRACT:
The invention relates to a process for the metallization of nucleic acids, comprising providing tris(hydroxymethyl)phosphine-Au (THP-Au) particles or derivatives thereof, binding said THP-Au particles to a nucleic acid to produce a metal nanoparticle-nucleic acid composite, and treatment of the metal nanoparticle-nucleic acid composite with an electroless plating solution. The invention further relates to a metallized nucleic acid obtainable according to such a method and a nanowire including a method for the manufacture of a nanowire.

REFERENCES:
patent: WO 97 48837 (1997-12-01), None
patent: WO 99 04440 (1999-01-01), None
Harker, C.S.W. et al., “Studies on the interaction of gold(i) phosphines with 2-thiouracil. Related studies with silver(i) phosphines”, Inorg. Chim. Acta, vol. 181, pp. 23-30 (1991).*
Mbindyo J K N et al: “DNA-Directed Assembly of Gold Nanowires on Complementary Surfaces” Advanced Materials, VCH Verlagsgesellschaft, Weinheim, DE, vol. 13, No. 4, Feb. 19, 2001, pp. 249-254, XP001004980.
Mirkin C A et al: “A DNA-Based Method for Rationally Assembling Nanoparticles Into Macroscopic Materials” Nature, vol. 382, Aug. 15, 1996, pp. 607-609, XP002186730.
Richter J et al: “Nanoscale Palladium Metallization of DNA” Advanced Materials, VCH Verlagsgesellschaft, Weinheim, DE, vol. 12, No. 7, Apr. 4, 2000, pp. 507-510, XP000949756.
Braun E et al: “DNA-Templated Assembly and Electrode Attachment of a Conducting Silver Wire” Nature, Macmillan Magazines, US, vol. 6669, No. 391, pp. 775-778, XP002079216.
Berning D E et al: “Au-Labeled Hydroxymethyl Phosphines as Models for Potential Therapeutic Pharmaceuticals-Production and Decay Property Considerations” Nuclear Medicine and Biology, Elsevier Science Publishers, New York, NY, US, vol. 25, No. 6, Aug. 1, 1998, pp. 577-583, XP004133349.

Affiliated with

Also associated with

Rating

Metallization of nucleic acids via metal nanoparticles... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Metallization of nucleic acids via metal nanoparticles..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Metallization of nucleic acids via metal nanoparticles... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3373153