Metal ion specific capacity affinity sensor

Chemistry: analytical and immunological testing – Metal or metal containing

Reexamination Certificate

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C422S082010, C422S082020, C422S082030, C422S082040, C422S082050, C422S051000, C436S080000, C436S081000, C436S082000, C436S083000, C436S084000, C436S149000, C436S150000

Reexamination Certificate

active

06933153

ABSTRACT:
This invention relates to a metal ion specific capacitance sensor with exceptional sensitivity and wide operating range. It is versatile because different kinds of recognition elements can be immobilized directly in a self-assembling monolayer substantially completely covering the surface of the measuring noble metal electrode. The electrode then becomes selective to those metal ions in the solution that show affinity to the recognition element on the surface. Compared to previously described electrochemical sensors, the sensor according to the present invention shows many orders of magnitude better sensitivity because of the unique measuring principle.

REFERENCES:
patent: 4964972 (1990-10-01), Sagiv et al.
patent: 5498538 (1996-03-01), Kay et al.
patent: 5500351 (1996-03-01), Eccles et al.
patent: 5594115 (1997-01-01), Sharma
patent: 5935823 (1999-08-01), Fowlkes et al.
patent: 5972656 (1999-10-01), Lopez et al.
patent: 6111079 (2000-08-01), Wylie et al.
patent: 6306584 (2001-10-01), Bamdad
patent: 6391590 (2002-05-01), Sano et al.
patent: 260 948 (1988-04-01), None
Schlereth, D. D. et al, Journal of Electroanalytical Chemistry 1997, 431, 285-295.
Liu, J. et al, Israel Journal of Chemistry 1997, 37, 235-239.
Mirsky, V. M. et al, Biosensors & Bioelectronics 1997, 12, 977-989.
Rickert, J. et al, Biosensors & Bioelectronics 1996, 11, 757-768.
Dong, X.-D. et al, Bioelectrochemistry and Bioenergetics 1997, 42, 63-69.
Madoz, J. et al, Journal of the American Chemical Society 1997, 119, 1043-1051.
Shen, H. et al, Journal of Solid State Electrochemistry 1997, 1, 148-154.
Nakano, K. et al, Transactions of the Materials Research Society of Japan 1994, 15A, 635-638.
Duan, C. et al, Analytical Chemistry 1994, 66, 1369-1377.
Steinberg, S. et al, Thin Films 1995, 20, 183-205.
Duan, C. et al, Mikrochimica Acta 1995, 117, 195-206.
Mattiason, B. et al, Journal of Applied Biochemistry 1979, 1, 377-384.
Sabatani, E. et al, Journal of Physical CHemistry 1987, 91, 6663-6669.
Rubinstein, I. et al, Nature 1988, 332, 426-429.
Cheng, Q. et Al, Analytical Chemistry 1992, 64, 1998-2000.
Frantz, B. et al, Biochemistry 1990, 29, 4747-4751.
Tommey, A. M. et al, FEBS Letters 1991, 292, 48-52.
Huckle, J. W. et al, Molecular Microbiology 1993, 7, 177-187.
Berggren, C. et al, Analytical Chemistry 1997, 69, 3651-1657.
Henke et al., “Self-Assembled Monolayers of Monofunctionalized Cyclodextrins onto Gold: A Mass Spectrometric Characterization and Impedance Analysis of Host-Guest Interaction,”Anal. Chem. 68:3158-3165, 1996.
Radloff et al., “Stability Improvement of an Optochemical Heavy Metal Ion Sensor by Covalent Receptor Binding,”Chemical Abstracts 126(8):1343, Abstract No. 112425u, 1997.
Radloff et al., “Stability Improvement of an Optochemical Heavy Metal Ion Sensor by Covalent Receptor Binding,”Sensors and Actuators B 35-36:207-211, 1996.
Rojas et al., “Supported Monolayers Containing Preformed Binding Sites. Synthesis and Interfacial Binding Properties of a Thiolated β-Cyclodextrin Derivative,”J. Am. Chem. Soc. 117:336-343, 1995.
Steinberg et al., “Ion-Selective Monolayer Membranes Based upon Self-Assembling Tetradentate Ligand Monolayers on Gold Electrodes. 2. Effect of Applied Potential on Ion Binding,”J. Am. Chem. Soc. 113:5176-5182, 1991.

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