Metal hydroxide scintigraphic agents and method of preparation

Details Metal hydroxide scintigraphic agents and method of preparation Metal hydroxide scintigraphic agents and method of preparation

1975-11-07

1977-11-08

Schafer, Richard E.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23293A, 23305F, 423 93, 423142, 2523011S, A61K 4300, A61K 2900

Patent

active

040576167

ABSTRACT:
Metal hydroxides such as Fe(OH).sub.2, Fe(OH).sub.3 and Sn(OH).sub.2 are prepared in the form of spherical particles of uniform and controlled size suitable for tagging with a radioactive element such as technetium-99m. Aqueous suspensions of such tagged particles are useful in scintigraphy as lung scanning agents.

REFERENCES:
patent: 3493514 (1970-02-01), Ashby
patent: 3634558 (1972-01-01), Stober
patent: 3937668 (1976-02-01), Zolle
Webber et al., "Demonstration of Thrombophlebitis and Endothelial Damage by Scintiscanning," in Radiology, 100: 93-97, 1971.
Zolle et al., "Preparation of Metabolizable Radioactive Human Serum Albumin Microspheres for Studies of the Circulation," Int. J. App. Radiat. & Iso. 21: 155-167 (1970).
Singh, et al., "Te-Iron Hydroxide Aggregates: A Radiopharmaceutical for Lung Scanning," J. Nuc. Med. 25(4): 283-286, 1971.

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