Metal hydroxide microspheroidal scintigraphic agents and method

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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2523011S, 250303, A61K 4300

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active

039624129

ABSTRACT:
Metal hydroxides such as Fe(OH).sub.2, Fe(OH).sub.3 and Sn(OH).sub.2 are prepared in the form of spherical particles of uniform and controlled size suitable for tagging with a radioactive element such as technetium-99m. Aqueous suspensions of such tagged particles are useful in scintigraphy as lung scanning agents.

REFERENCES:
webber, M. et al., Demonstration of Thrombophlebitis and Endothelial Damage by Scintiscanning, Radiology, vol. 100, July, 1971, pp. 93-97.
Darter, E. et al., Improved Binding and Stability of 99m Tc-Iron Hydroxide, In J. Nuclear Medecine 12: pp. 632-643, Sept. 1971.
Yano, Y. et al., 99m Tc-Ferric Hydroxide Macroaggregates for Pulmonary Scintiphotography, In J. Nuc. Med. 10: pp. 683-686, Nov. 1969.
Zolle, I. et al., Preparation of Metabolizable Radioactive Human Serum Albumin Microspheres for Studies of the Circulation, In Int. J. App. Rad. and Iso. 21: pp. 155-167, 1970.

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