Metal-free buffer for ion selective electrode-based assays

Details Metal-free buffer for ion selective electrode-based assays Metal-free buffer for ion selective electrode-based assays

1990-06-08

1992-12-29

Tung, T.

Chemistry: electrical and wave energy

Processes and products

Processes of treating materials by wave energy

20415313, 20415315, 204416, 204418, 436 18, 436 68, 436 74, 436 79, 436125, G01N 27333

Patent

active

051748720

ABSTRACT:
A heavy metal-free composition and its method of use in an ion selective electrode-based assay are disclosed. The heavy metal-free composition includes a borate compound and an alkalinity adjusting compound, and is used to dilute a test sample; buffer the test sample; and substantially reduce the effects of interferents present in the test sample on the ion selective electrode-based assay. The heavy metal-free composition and its method of use are especially useful in an ion selective electrode-based assay for carbonate ion concentration in a test sample, like blood serum, blood plasma, urine or cerebrospinal fluid.

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"Handbook of Chemistry and Physics", 52nd Edition, p. D-104, (1971).
J. Bagg, Anal. Chem., vol. 48, No. 12, pp. 1811-1812, Oct. 1976.

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