Metal containing 8-hydroxyquinoline chelating agents

Details Metal containing 8-hydroxyquinoline chelating agents Metal containing 8-hydroxyquinoline chelating agents

1991-05-21

1993-09-14

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540474, 540470, 546178, 546180, 546 2, A61K 4300, A61K 2900, G01T 116, C07D40302, C07D40306

Patent

active

052450260

ABSTRACT:
The present invention provides linear, cyclic and trifurcate tri- and tetramine backbone multidentate chelating agents based on the 8-hydroxyquinoline chelating unit. The chelating agents may optionally be substituted with a substrate reactive moiety and antibody-metal ion conjugates may be produced for in vivo diagnostic and therapeutic methods.

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