Metal compounds, mixed or sulphated, as phosphate binders

Details Metal compounds, mixed or sulphated, as phosphate binders Metal compounds, mixed or sulphated, as phosphate binders

2005-08-09

2005-08-09

Langel, Wayne A. (Department: 1754)

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Heavy metal or compound thereof

C423S263000, C423S420200, C423S463000, C423S518000, C423S594200

Reexamination Certificate

active

06926912

ABSTRACT:
A non-aluminum containing mixed metal compound for pharmaceutical use, which may, for example, be a mixed metal hydroxy carbonate containing magnesium and iron, and may have a hydrotalcite structure, preferably a non-aged hydrotalcite structure. Other metals, including, for example, calcium, lanthanum and cerium, may also be used. Metal sulphate compounds, especially calcium sulphate, lanthanum sulphate and/or cerium sulphate, compounds are also useful. The mixed metal compounds have a phosphate binding capacity of at least 30%, by weight, based on the test methods 1, 2 or 3, described in the specification, over a pH range from 3 to 7, such as from 2 to 8. The compound is especially useful in the treatment of hyperphosphataemia.

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