Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Reexamination Certificate
2005-07-12
2005-07-12
Hartley, Michael G. (Department: 1616)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
C424S009361, C424S009363, C424S009365, C424S001650, C424S009400
Reexamination Certificate
active
06916461
ABSTRACT:
The invention relates to new, monomeric, perfluoroalkyl-substituted metal complexes, processes for their production, and their use in diagnosis and therapy.The compounds according to the invention are suitable especially as in vivo contrast media in nuclear spin tomography (MRT). They can preferably be used as blood-pool agents and as lymphographic agents.
REFERENCES:
patent: 4859584 (1989-08-01), Horan et al.
patent: 5248498 (1993-09-01), Neumann et al.
patent: 5401493 (1995-03-01), Lohrmann et al.
patent: 5496536 (1996-03-01), Wolf
patent: 5536491 (1996-07-01), Asai et al.
patent: 5672334 (1997-09-01), Ranney
patent: 5690909 (1997-11-01), Platzek et al.
patent: 43 17 588 (1994-12-01), None
patent: 0 266 195 (1987-10-01), None
patent: 0 266 196 (1987-10-01), None
patent: 0 592 306 (1994-04-01), None
Gong et al.,Magn. Reson Imaging, vol. 9, No. 1 (1991) pp. 101-106: “Paramater Optimization and Callbration of Fluorine-19 Magnetic Resonance Imaging at 1.5 Tesia”.
Lee et al.,J. Magn. Reson Imaging, vol. 4, No. 4 (1994), pp. 609-613: “In Vivo Fluorine-19 MR Imaging: Relaxation Enhancement with Gd-DTPA”.
Ratner et al.,Invest Radiol., vol. 24, No. 3 (1989), pp. 224-227: “Fluorine-19 Relaxation Rate Enhancement and Frequency Shift with Gadolinium-DTPA”.
Thomas et al.,J. Magn. Reson Imaging, vol. 4, No. 4 (1994), pp. 631-635: “Evaluation of the influence of the Aqueous Phase Bioconstituent Environment on the F-19 T1 of Perfluorocarbon Blood Substitute Emulstions”.
International Search Report, Norwegian, Nov. 14, 2001.
Ebert Wolfgang
Frenzel Thomas
Misselwitz Bernd
Niedballa Ulrich
Platzek Johannes
Hartley Michael G.
Millen White Zelano & Branigan P.C.
Schering AG
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