Metal chelating lipids which are useful as sensors in fluorometr

Details Metal chelating lipids which are useful as sensors in fluorometr Metal chelating lipids which are useful as sensors in fluorometr

1996-09-11

1998-11-17

Adams, Donald E.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Means for analyzing liquid or solid sample

562444, 540474, G01N 2164, C07C22934, C07D25502

Patent

active

058372024

ABSTRACT:
An fluorescent metal-chelating amphiphile having the structure: ##STR1## wherein A is a hydrophobic fluorophore, X and Y are aliphatic hydrocarbons having from 9 to 25 carbon atoms, B is a hydrophilic spacer, C is a metal chelator, and L is either an ether or ester linkage.
The fluorescent metal-chelating amphiphile is combined with a matrix lipid to form lipid-based sensors which provide fluorometric detection of metal ions in liquids.

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