Metal chelate conjugated monoclonal antibodies

Chemistry: analytical and immunological testing – Involving production or treatment of antibody – Monoclonal antibody

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436804, 436819, 436813, 436811, 260429J, 424 11, 424 9, 424 85, 424 86, A61K 3900, A61K 3942, A61K 4300, A61K 4900

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active

044725094

ABSTRACT:
Methods of manufacturing and purifying metal chelate conjugated monoclonal antibodies are described. The chelated metal may be one which emits alpha, beta or gamma radiation, or positrons. Alternatively, the metal can be one which is fluorogenic or paramagnetic. The conjugates are suited for diagnostic and therapeutic uses.

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