Metal catalyzed displacement process

Details Metal catalyzed displacement process Metal catalyzed displacement process

1995-06-02

1997-10-28

Cook, Rebecca

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540350, C07D49900, C07D48704

Patent

active

056819510

ABSTRACT:
A process for preparing a compound of formula (I'): ##STR1## comprising reacting a compound of formula (II'): ##STR2## with a compound of formula (III'):

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Cabiddu et al, Annali di Chimica, 62, 505-512 1972.
Rao et al, Heteroatom Chemistry, 3(1), 25-31 1992.
Fetter, et al, J. Chem. Research, Synopses 2, Feb. 28-29 1987.
Sowin, et al, "Enantioselective Synthesis of the 1.beta.-Methylcarbapenems via Cycloaddition of 3-Siloxypentadiene and 4-Acetoxyazetidinone", J.A.C.S., 53, 4154 (1988).
Guthikonda et al, "Structure-Activity Relationships in the 2-Arylcarbapenem Series: Synthesis of 1-Methyl-2-arylcarbapenems", J. Med. Chem., 30, 871 (1987).
Kim et al, "Stereoselective Synthesis of 1-.beta.-Methylcarbapenem", Tetrahedron Letters, 28, 507-510 (1987).

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