Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2007-03-19
2009-11-03
Allen, Marianne P (Department: 1647)
Chemistry: molecular biology and microbiology
Vector, per se
C536S023400, C530S324000, C435S069700
Reexamination Certificate
active
07611893
ABSTRACT:
The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a condition of cellular stress. The methods of the invention may be used for therapeutic or diagnostic purposes.
REFERENCES:
patent: 4683202 (1987-07-01), Mullis
patent: 5824467 (1998-10-01), Mascarenhas
patent: 5861273 (1999-01-01), Olson et al.
patent: 5914254 (1999-06-01), Mascarenhas et al.
patent: 6087090 (2000-07-01), Mascarenhas
patent: 6251639 (2001-06-01), Kurn
patent: 6630160 (2003-10-01), Evans et al.
patent: 6692918 (2004-02-01), Kurn
patent: 6914049 (2005-07-01), Mascarenhas
patent: 2003/0059430 (2003-03-01), Mascarenhas
patent: 2003/0161829 (2003-08-01), Mascarenhas
patent: 2003/0224990 (2003-12-01), Mascarenhas
patent: 2007/0134257 (2007-06-01), Mascarenhas
patent: 2008/0039393 (2008-02-01), Mascarenhas
patent: 2009/0053203 (2009-02-01), Mascarenhas
Alvarez Garcia, B. et al. (Nov. 2003). “High-Sensitivity C-Reactive Protein in High-Grade Carotid Stenosis: Risk Marker for Unstable Carotid Plaque,”Journal of Vascular Surgery38(5):1018-1024.
Ambrosini, G. et al. (Aug. 1997). “A Novel Anti-Apoptosis Gene, Survivin, Expressed in Cancer and Lymphoma,”Nature Medicine3(8):917-921.
Anderson, R.L. et al. (1981). “Temperature-Induced Homeoviscous Adaptation of Chinese Hamster Ovary Cells,”Biochimica et Biophysica Acta641:334-348.
Antman, K.H. et al. (Nov. 10, 1999). “High-Dose Chemotherapy for Breast Cancer,”JAMA282(18):1701-1703.
Aramburu, J. et al. (Sep. 24, 1999). “Affinity-Driven Peptide Selection of an NFAT Inhibitor More Selective Than Cyclosporin A,”Science285:2129-2133.
Arany, E. et al. (1996). “Rapid Clearance of Human Insulin-Like Growth Factor Binding Protein-3 From the Rat Circulation and Cellular Localization in Liver, Kidney and Stomach,”Growth Regulation6:32-41.
Armas, A. et al. (2006). “Zinc(II) Binds to the Neuroprotective Peptide Humanin,”Journal of Inorganic Biochemistry100:1672-1678.
Arteaga, E. et al. (Dec. 2005). “Plasma Amino-Terminal Pro-B-Type Natriuretic Peptide Quantification in Hypertrophic Cardiomyopathy,”American Heart Journal150(6):1228-1232.
Barile, G.R. et al. (Aug. 2005). “The RAGE Axis in Early Diabetic Retinopathy.”Investigative Ophthalmology&Visual Science46(8):2916-2924.
Barnes, J.A. et al. (2001). “Expression of Inducible Hsp70 Enhances the Proliferation of MCF-7 Breast Cancer Cells and Protects Against the Cytotoxic Effects of Hyperthermia,”Cell Stress Chaperones6(4):316-325.
Barsyte-Lovejoy, D. et al. (Mar. 22, 2002). “Specificity Determinants in MAPK Signaling to Transcription Factors,”The Journal of Biological Chemistry277(12):9896-9903.
Benaki, D. et al. (2005). “Solution Structure of Humanin, a Peptide Against Alzheimer's Disease-Related Neurotoxicity,”Biochemical and Biophysical Research Communications329:152-160.
Benaki, D. et al. (2006). “Solution Structure of Ser14Gly-humanin, a Potent Rescue Factor Against Neuronal Cell Death in Alzheimer's Disease,”Biochemical and Biophysical Research Communications349:634-642.
Bosio, A. et al (2002). “Kinetics of Gene Expression Profiling in Swiss 3T3 Cells Exposed to Aqueous Extracts of Cigarette Smoke,”Carinogenesis23(5):741-748.
Butcher, J. (Feb. 2005). “Parkin Gene Therapy Could Treat Parkinson's Disease,”Lancet Neurol.4:82.
Butt, A.J. et al. (Jul. 2005). “Enhancement of Tumor Necrosis Factor-Alpha-Induced Growth Inhibition by Insulin-Like Growth Factor-Binding Proteins-5 (IGFBP-5), But Not IGBFP-3 in Human Breast Cancer Cells,”Endocrinology146(7):3113-3122.
Campisi, J. et al. (2003). “Stress-Induced Extracellular Hsp72 is a Functionally Significant Danger Signal to the Immune System,”Cell Stress&Chaperones8(3):272-286.
Cavasin, M.A. (May 2004). “Prolyl Oligopeptidase is Involved in Release of the Antifibrotic Peptide Ac-SDKP,”Hypertension43:1140-1145.
Cavasin, M.A. (2006). “Therapeutic Potential of Thymosin-β4 and its Derivative N-Acetyl-Seryl-Aspartyl-Lysyl-Proline (Ac-SDKP) in Cardiac Healing After Infarction,”Am. J. Cardiovasc. Drugs6(5):305-311.
Chiba, T. et al. (Nov. 2, 2005). “Development of a Femtomolar-Acting Humanin Derivative Named Colivelin by Attaching Activity-Dependent Neurotrophic Factor to Its N Terminus: Characterization of Colivelin-Mediated Neuroprotection Against Alzheimer's Disease-Relevant Insults in Vitro and in Vivo,”The Journal of Neuroscience25(44):10252-10261.
Chong, Y-P. et al. (Sep. 2005). “C-Terminal Src Kinase (CSK) and CSK-Homologous Kinase (CHK)—Endogenous Negative Regulators of Src-Family Protein Kinases,”Growth Factors23(3):233-244.
Ciocca, D.R. et al. (Oct. 6, 1993). “Biological and Clinical Implications of Heat Shock Protein 27000 (Hsp27): a Review,”Journal of National Cancer Institute85(19):1558-1570.
Ciocca, D.R. et al. (2002). “Hsp27 as a Prognostic and Predictive Factor in Cancer,”In Small Stress Proteins. A.-P. Arrigo et al. eds., Springer-Verlag Berlin Heidelberg, pp. 205-218.
Clemmons, D.R. et al. (Jan. 2005). “Interaction Between Insulin-Like Growth Factor-I Receptor and alphaVbeta3 Integrin Linked Signaling Pathways: Cellular Responses to Changes in Multiple Signaling Inputs,”Molecular Endocrinology19(1):1-11.
Cohen, M.P. et al. (2002). “Inhibiting Albumin Glycation in Vivo Ameliorates Glomerular Overexpression of TGF-β1,”Kidney International61:2025-2032.
Cohen, M.P. et al. (2005). “Evidence Linking Glycated Albumin to Altered Glomerular Nephrin and VEGF Expression, Proteinuria, and Diabetic Nephropathy,”Kidney International68:1554-1561.
Cornford, P.A. et al. (Dec. 15, 2000). “Heat Shock Protein Expression Independently Predicts Clinical Outcome in Prostate Cancer,”Cancer Research60:7099-7105.
Darios, F. et al. (2003). “Parkin Prevents Mitochondrial Swelling and Cytochrome C Release in Mitochondria-Dependent Cell Death,”Human Molecular Genetics12(5):517-526.
Dessein, P.H. et al. (2002). “Cardiovascular Risk in Rheumatoid Arthritis Versus Osteoarthritis: Acute Phase Response Related Decreased Insulin Sensitivity and High-Density Lipoprotein Cholesterol as Well as Clustering of Metabolic Syndrome Features in Rheumatoid Arthritis,”Arthritis Research4(5):1-6.
Driscoll, M. et al. (Mar. 2003). “Dying For a Cause: Invertebrate Genetics Takes On Human Neurodegeneration,”Nature Reviews Genetics4:181-194.
Escobar-Morreale, H.F. et al. (Feb. 2004). “Serum Interleukin-18 Concentrations Are Increased in the Polycystic Ovary Syndrome: Relationship to Insulin Resistance and to Obesity,”The Journal of Clinical Endocrinology&Metabolism89(2):806-811.
Firestein, G.S. (May 15, 2003). “Evolving Concepts of Rheumatoid Arthritis,”Nature423:356-361.
Gargalovic, P. et al. (2003). “Cellular Apoptosis is Associated With Increased Caveolin-1 Expression in Macrophages,”Journal of Lipid Research44:1622-1632.
Gobert, A.P. et al. (Jan. 2, 2004). “Helicobacter Pylori Heat Shock Protein 60 Mediates Interleukin-6 Production by Macrophages via a Toll-Like Receptor (TLR)-2-,TLR-4-, and Myeloid Differentiation Factor 88-Independent Mechanism,”The Journal of Biological Chemistry279(1):245-250.
Goldberg, M.S. et al. (Oct. 31, 2003). “Parkin-Deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons,”The Journal of Biological Chemistry278(44):43628-43635.
Gordon, M.S. et al. (2005). “Managing Patients Treated with Bevacizumab Combination Therapy,”Oncology69(Suppl 3):25-33.
Harkins, M.S. et al. (Dec. 2003). “Regulation of CD23 in the Chronic Inflammatory Response in Asthma: A Role For Interferon-y and Heat-Shock Protein 70 in the T
Allen Marianne P
Morrison & Foerster / LLP
Ontherix, Inc.
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