Metal-binding compounds and uses therefor

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C530S329000, C530S330000, C530S328000

Reexamination Certificate

active

07632803

ABSTRACT:
The invention provides a method of reducing the damage done by reactive oxygen species (ROS) in an animal. The invention also provides a method of reducing the concentration of a metal in an animal. These methods comprise administering to the animal an effective amount of a metal-binding compound as further described in the application. The invention further provides a method of reducing the damage done by ROS to a cell, a tissue or an organ that has been removed from an animal. This method comprising contacting the cell, tissue or organ with a solution or medium containing an effective amount of a metal-binding compound of the invention. The invention further provides novel metal-binding compounds, pharmaceutical compositions comprising the metal-binding compounds, and kits comprising a container holding a metal-binding compound of the invention.

REFERENCES:
patent: 3853838 (1974-12-01), Greven
patent: 3862928 (1975-01-01), De Wied et al.
patent: 4025499 (1977-05-01), Thomas
patent: 4046633 (1977-09-01), Keutel
patent: 4085096 (1978-04-01), Tinney et al.
patent: 4323558 (1982-04-01), Nelson
patent: 4412988 (1983-11-01), Gasc et al.
patent: 4438029 (1984-03-01), Erickson et al.
patent: 4461724 (1984-07-01), Konishi
patent: 4591648 (1986-05-01), Jones et al.
patent: 4628045 (1986-12-01), Hahn
patent: 4665054 (1987-05-01), Pickart
patent: 4684624 (1987-08-01), Hosobuchi et al.
patent: 4725576 (1988-02-01), Pollock et al.
patent: 4746649 (1988-05-01), Raddatz et al.
patent: 4760051 (1988-07-01), Pickart
patent: 4767753 (1988-08-01), Pickart
patent: 4810693 (1989-03-01), Pickart
patent: 4816449 (1989-03-01), Hahn
patent: 4877770 (1989-10-01), Pickart
patent: 4880778 (1989-11-01), Bowers et al.
patent: 4912118 (1990-03-01), Hider et al.
patent: 4952395 (1990-08-01), Shinnick et al.
patent: 4975423 (1990-12-01), Gaffar
patent: 5023237 (1991-06-01), Pickart
patent: 5051406 (1991-09-01), Satoh
patent: 5059537 (1991-10-01), Pedroni et al.
patent: 5059588 (1991-10-01), Pickart
patent: 5087696 (1992-02-01), Parker et al.
patent: 5101041 (1992-03-01), Troutner et al.
patent: 5104865 (1992-04-01), Hider et al.
patent: 5118665 (1992-06-01), Pickart
patent: 5120831 (1992-06-01), Pickart
patent: 5135913 (1992-08-01), Pickart
patent: 5145838 (1992-09-01), Pickart
patent: 5148540 (1992-09-01), Beardsley et al.
patent: 5149540 (1992-09-01), Kunihiro et al.
patent: 5158884 (1992-10-01), Conti-Tronconi et al.
patent: 5164367 (1992-11-01), Pickart
patent: 5177061 (1993-01-01), Pickart
patent: 5200320 (1993-04-01), Sette et al.
patent: 5214032 (1993-05-01), Pickart
patent: 5227307 (1993-07-01), Bar-Or et al.
patent: 5252559 (1993-10-01), Kronholm et al.
patent: 5256559 (1993-10-01), Maraganore et al.
patent: 5270447 (1993-12-01), Liotta et al.
patent: 5290519 (1994-03-01), Bar-Or et al.
patent: 5348943 (1994-09-01), Pickart
patent: 5380747 (1995-01-01), Medford et al.
patent: 5382431 (1995-01-01), Pickart
patent: 5422096 (1995-06-01), Lauffer et al.
patent: 5455229 (1995-10-01), Hahn et al.
patent: 5470876 (1995-11-01), Proctor
patent: 5476939 (1995-12-01), Johnson
patent: 5503987 (1996-04-01), Wagner et al.
patent: 5527522 (1996-06-01), Lauffer et al.
patent: 5529907 (1996-06-01), Nierman et al.
patent: 5538945 (1996-07-01), Pallenberg et al.
patent: 5550183 (1996-08-01), Pickart
patent: 5554375 (1996-09-01), Pickart
patent: 5585466 (1996-12-01), Carter
patent: 5591711 (1997-01-01), Koyama et al.
patent: 5618785 (1997-04-01), Heavner et al.
patent: 5624900 (1997-04-01), Suda et al.
patent: 5628982 (1997-05-01), Lauffer et al.
patent: 5631172 (1997-05-01), Johnson
patent: 5637311 (1997-06-01), Pallenberg
patent: 5637578 (1997-06-01), Riley et al.
patent: 5639624 (1997-06-01), Wagner et al.
patent: 5650134 (1997-07-01), Albert et al.
patent: 5650307 (1997-07-01), Sijmons et al.
patent: 5654160 (1997-08-01), Johnson
patent: 5663301 (1997-09-01), Johnson
patent: 5670627 (1997-09-01), Johnson
patent: 5670645 (1997-09-01), Johnson
patent: 5683907 (1997-11-01), Johnson
patent: 5710123 (1998-01-01), Heavner et al.
patent: 5710172 (1998-01-01), Kukreja et al.
patent: 5739395 (1998-04-01), Bergeron, Jr.
patent: 5770178 (1998-06-01), Itaya et al.
patent: 5776892 (1998-07-01), Counts et al.
patent: 5780594 (1998-07-01), Carter
patent: 5785948 (1998-07-01), Itaya et al.
patent: 5786335 (1998-07-01), Cody et al.
patent: 5807535 (1998-09-01), Smith et al.
patent: 5858993 (1999-01-01), Pickart
patent: 5874573 (1999-02-01), Winchell et al.
patent: 5877277 (1999-03-01), Coy et al.
patent: 5888522 (1999-03-01), Pickart
patent: 5906996 (1999-05-01), Murphy
patent: 5919900 (1999-07-01), Moyle et al.
patent: 5922761 (1999-07-01), Lai
patent: 5932548 (1999-08-01), Deghenghi
patent: 5994339 (1999-11-01), Crapo et al.
patent: 6001965 (1999-12-01), Livant
patent: 6004953 (1999-12-01), Volpin et al.
patent: 6008205 (1999-12-01), Serhan et al.
patent: 6017888 (2000-01-01), Pallenberg et al.
patent: 6022879 (2000-02-01), Crow et al.
patent: 6083758 (2000-07-01), Imperiali et al.
patent: 6084093 (2000-07-01), Riley et al.
patent: 6264966 (2001-07-01), Winchell et al.
patent: 6348465 (2002-02-01), Baker
patent: 6399371 (2002-06-01), Falduto et al.
patent: 6566511 (2003-05-01), Revenkova et al.
patent: 6579891 (2003-06-01), Fernandez-Pol
patent: 6583182 (2003-06-01), Winchell et al.
patent: 6610693 (2003-08-01), Baker
patent: 6610821 (2003-08-01), Blaschuk et al.
patent: 6800450 (2004-10-01), Rosén et al.
patent: 6897243 (2005-05-01), Baker et al.
patent: 2002/0037827 (2002-03-01), Wang et al.
patent: 2003/0060408 (2003-03-01), Bar-Or et al.
patent: 2003/0130185 (2003-07-01), Bar-Or et al.
patent: 2005/0159489 (2005-07-01), Baker et al.
patent: 327263 (1989-11-01), None
patent: 719790 (1995-12-01), None
patent: 0613560 (1998-10-01), None
patent: 62116565 (1987-05-01), None
patent: WO 91/17760 (1991-11-01), None
patent: WO 93/10459 (1993-05-01), None
patent: WO 93/23425 (1993-11-01), None
patent: WO 94/09808 (1994-05-01), None
patent: WO 94/14836 (1994-07-01), None
patent: WO 94/26295 (1994-11-01), None
patent: WO 95/26744 (1995-10-01), None
patent: WO 97/44313 (1997-11-01), None
patent: WO 97/49409 (1997-12-01), None
patent: WO 98/40071 (1998-09-01), None
patent: WO 98/54138 (1998-12-01), None
patent: WO 99/39706 (1999-08-01), None
patent: WO 99/45907 (1999-09-01), None
patent: WO 00/13712 (2000-03-01), None
patent: WO 00/18392 (2000-04-01), None
patent: WO 00/20454 (2000-04-01), None
patent: WO 00/20840 (2000-04-01), None
patent: WO 00/21941 (2000-04-01), None
patent: WO 00/23469 (2000-04-01), None
patent: WO 00/36136 (2000-06-01), None
patent: WO 01/79444 (2001-10-01), None
patent: WO 02/43722 (2002-06-01), None
patent: WO 02/064621 (2002-08-01), None
Valadon (J. Immunol 161, 1829-36, 1998).
U.S. Appl. No. 09/678, 202, filed Sep. 29, 2000, Bar-Or et al.
Adman, “Copper Protein Structures,”Advances in Protein Chemistry, 42:145-197 (1991).
Adman,Advances in Protein Chemistry, 42:145-197 (1991).
Afans'ev, Superoxide Ion: Chemistry and Biological Implications, vol. I, pp. 26, 51, 147, 168-196, 248-266 (CRC Press, Boca Raton, FL) (1989).
Aitken,Mol. Biotech., 12:241-253 (1999).
Ames et al.,Proc. Natl. Acad. Sci. USA, 90:7915-7922(1993).
“Angiogenesis Inhibitors,” found at http://www.cancerprotocol.com/angiogenesis—inhbitiors.html, Jan. 28, 2002, 1 page.
Atanasiu et al.,Mol. Cell. Biochem., 189:127-135 (1998).
Atwood et al.,J. Biol. Chem., 273(21):12817-12826 (1998).
Aust,Bibl. Nutr. Dieta. Basel, Karger, No. 43, pp. 266-277 (1989).
Bal et al.,Chem. Res. Toxicol., 10:915-921 (1997).
Bal et al.,Chem. Res. Toxicol., 10(8):906-914 (1997).
Bar-Or et al.,Biochem. Biophys. Res. Commun., 282:356-360 (2001).
Bar-Or et al.,Biochem. Biophys. Res. Commun., 284:856-862 (2001).
Bar-Or et al., text of poster presented at 17th American Peptide Symposium, San Diego, California, Jun. 2001, found at http://www.5z.com/aps/, Feb. 19, 2002.
Bar-Or et al.,Biochem. Biophys. Res. Commun., 290:1388-1392 (2002).
Bar-Or et al.,Free Rad. Biol. Med., 32(2):197-199 (2002).
Bar-Or et al., abstr. P416 in American Peptide Soci

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