Metachromatic dye sorption means for differential determination

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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8644, 8657, 436 63, 436 64, 424 71, G01N 130, G01N 3348, G01N 3352

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active

044003706

ABSTRACT:
In the diagnosis and prognosis of various diseases as well as medical researches in relation thereto studies leading to differentiation, identification, enumeration and following the variations in human blood, leukocytes play a vital role. Heretofore, accurate detailed lengthy and arduous procedures were essential to such ends, if available. In a parent case, of which this is a continuation-in-part, it was found selective use of certain basic quaternary, metachromatic dye staining by supravital techniques made possible instantaneous optical differentiation of the five major individual leukocyte species. Here further research has revealed that with but one of the species of the dye class above one can by the same techniques make the foregoing determinations with regard to specific leukocytes including promyelocytes, myelocytes, metamyelocytes, band cells, T-cells and B-cells as well as the neutrophils, eosinophils, basophils and monocytes of the parent disclosure.

REFERENCES:
patent: 2126852 (1938-08-01), Wolff
patent: 3560135 (1971-02-01), Yamayo
patent: 3617185 (1970-11-01), Drantz
patent: 3985500 (1976-10-01), Streck
Gurr, Synthetic Dyes in Biol., Med. & Chem., Aid Press, N.Y., 1971, pp. 54-55, 99, 117, 147-149, 395, 805.
Connis, Biological Stains, Williams & Wilkins, Balto, 9th Ed., 1977, pp. 43, 368, 404-407, 415-429.
Gray, Ency. of Microscop. & Michrotech, Van Nostrand-Reinhold Co., N.Y., 1973, pp. 398-399, 469, 561, 563.
Humdson, Animal Tissue & Tech., W. H. Freeman & Co., San Francisco, 1972, pp. 128-132.
Ruddell, Chem. Abs., vol. 89, 1978, Abst. #89: 54252q; Chem. Sub. Index, p. 2791cs.
Simpson, Stain Tech., vol. 45, No. 5, 1970, pp. 221-223.
MacConaill, Ireland J. Med. Sci., Jun. '64, pp. 243-250.
Sabin Bull., Johns Hopkins U., vol. XXXIV, #391, Sep. 1923, pp. 277-288.
Spiridonovitch, The Anatomical Record, vol. 27, Jan.-May 1924, pp. 367-373.
Moore, PSEMB, vol. 82, 1953, 601-603.
Hallberg, AEPA Med. Scand. Suppl., vol. 180, 1946, pp. 7-15.
Pilot, Use of Base Fluids for Counting Eosinophils, U. of Ill., May 23, 1950, pp. 870-871.

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