Metabotropic glutamate receptor protein and nucleic acid

Details Metabotropic glutamate receptor protein and nucleic acid Metabotropic glutamate receptor protein and nucleic acid

1998-08-30

2000-08-15

Spector, Lorraine

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

4352523, 43525411, 435 691, 4353201, 536 231, 536 235, 530350, C07K 14705, C12N 510, C12N 1512

Patent

active

061035246

ABSTRACT:
This invention describes a novel human glutamate receptor, designated mGluR6. This invention also encompasses nucleic acids encoding this receptor, or a fragment thereof, as well as methods employing this receptor and the nucleic acid compounds.

REFERENCES:
patent: 4992373 (1991-02-01), Bang et al.
patent: 5912122 (1999-06-01), Daggett et al.
Hashimoto et al., GenBank Accession No. U82083, The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6, Oct. 1997.
Nakajima et al., Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate, J. Biol. Chem., 268(16): 11868-11873, Jun. 1993.
Pin et al., Review: neutrotransmitter receptors I, Neuropharmacol., 34(1): 1-26, 1995.
Berg et al., High-level expression of secreted proteins from cells adapted to serum-free suspension culture, BioTechniques, 14(6):972-978, 1993.

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