Metabotropic glutamate receptor-5 modulators

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S302000, C544S127000, C546S115000

Reexamination Certificate

active

07087601

ABSTRACT:
Phenyl compounds substituted at the 1-position with a fused bicyclo moeity formed from a five-membered heterocycle fused to a six-membered carbocycle, to a six-membered aryl, or to a six-membered hetaryl, and further optionally substituted at the 3,4 positions, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, and panic, as well as in the treatment of pain and other diseases.

REFERENCES:
patent: 3458506 (1969-07-01), Bloom et al.
patent: 3899506 (1975-08-01), Shen et al.
patent: 4038396 (1977-07-01), Shen et al.
patent: 5077408 (1991-12-01), Guillaumet et al.
patent: WO 96 11917 (1996-04-01), None
patent: WO 02 51821 (2002-07-01), None
Bathini et al., “A convenient synthesis of substituted oxazolo[5,4-b]pyridines using lead tetraacetate as oxidative cyclizing agent,” Synthetic Communications (1991), 21(2), 215-22.
Flouzat et al., “A new convenient synthesis of 2-aryl- and 2-heteroaryloxazolo[5,4-b]pyridines,” Synthesis (1990), (1), 64-6.
Frazer et al., “Oxazolopyridines and oxazoloquinolines. I. 2′-Alkyland 2′-aryl derivatives of oxazolo[4′,5′,3,4]pyridine and oxazolo[4′,5′,3,4]quinoline,” Journal of the Chemical Society, Abstracts (1956), 1781-4.
Bathini, et al., Synthetic Communications, vol. 21 (2), pp. 215-22, 1991.
Flouzat, et al., Synthesis, vol. 1, pp. 64-6, 1990.
Frazer, et al., Journal of the Chemical Society, Abstracts, pp. 1781-4, 1956.

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