Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-02-08
1991-03-05
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514357, 546266, 546333, A61K 3144, C07D40106, C07D21170
Patent
active
049978420
ABSTRACT:
The present invention relates to the + or - pirmenol stereoisomers and to selected metabolites of pirmenol or (+,-)-cis-.alpha.-[3-(2,6-dimethyl-1-piperidinyl))propyl]-.alpha.-phenyl-2 -pyridinemethanol which are active as antiarrhythmic agents. The pharmacological use of the metabolites that is the present invention is as antiarrhythmic agents. Pharmaceutical compositions comprising the metabolites are also within the scope of the invention.
REFERENCES:
patent: 4112103 (1978-09-01), Fleming
CA 97(11):92158m.
Hodenberg Albrecht V.
Hurley Timothy R.
Klemisch Wolfgang
Schaller Egmont
Sherwood Dino A.
Haley Jacqueline
Lee Mary C.
Thierstein Joan
Warner-Lambert Co.
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