Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2008-03-25
2008-03-25
Weber, Jon (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S388200, C514S012200
Reexamination Certificate
active
10466376
ABSTRACT:
The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GMG-3, GMG-4, Cluster 1, GMG-6A, or GMG-6B polypeptides have been identified that are beneficial in the treatment of metabolic disorders. These compounds should be effective for reducing body mass and for treating metabolic-related diseases and disorders. These metabolic-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
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Database: EMBL: Accession No. P23435; Created Nov. 1, 1991, Description: Cerebellin precursor (Precerebellin) XP-002209555.
Database: EMBL: Accession No. Q96JF4; Created Dec. 1, 2001, Description: Hypothetical protein KIAA1873 (Fragment) XP-002209556.
Database EMBL: Accession No. Q15848; Created Nov. 1, 1997, Description: Adiponectin precursor (30 kDa adipocyte complement-related protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein) XP-002208112.
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Schäffler et al. “The Human apM-1, an Adipocyte-Specific Gene Linked to the Family of TNF's and to Genes Expressed in Activated T Cells, Is Mapped to Chromosome 1q21.3-q23, a Susceptibility Locus Identified for Familial Combined Hyperlipidaemia (FCH)”Biochemical and Biophysical Research Communications1999, vol. 260, pp. 416-425. XP-000867718.
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Bihain Bernard
Chicca Barbara A.
Erickson Mary Ruth
Tanaka Hiroaki
Mitra Rita
Saliwanchik Lloyd & Saliwanchik
Serono Genetics Institute S.A.
Weber Jon
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