Meta-substituted phenylene sulphonamide derivatives

Details Meta-substituted phenylene sulphonamide derivatives Meta-substituted phenylene sulphonamide derivatives

1997-03-27

1998-12-01

Huff, Sheela

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

568 29, 568 30, 568 31, A61K 3800

Patent

active

058439064

ABSTRACT:
The present invention relates to a class of compounds represented by the Formula I ##STR1## or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the .alpha..sub.v .beta..sub.3 integrin.

REFERENCES:
Fisher et al Endocrinology vol. 132 p. 1141, 1993.
Brooks et al Scinece vol. 264 p. 569, Apr. 1994.
Brooks et al Cell vol. 79 p. 1157, Dec. 1994.
Seftor et al PNAS vol. 89 p. 1557, Mar. 1992.

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