Mesylates of piperazine derivatives and process for their...

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

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C544S363000, C544S373000, C544S376000

Reexamination Certificate

active

07030241

ABSTRACT:
The invention relates to the mesylates of a group of piperazine derivatives and to a process for the preparation of these mesylates in an economic way in the high yield and of high purity. According to the process of the invention the synthesis of the piperazine ring and the mesylate formation are combined in a single reaction step. The invention relates to the mesylate of compounds of the formula (I) wherein X is a bicyclic heterocyclic phenyl group and Y is methyl, ethyl (optionally substituted with fluorine), cycloalkyl (3–7C) methyl, benzyl or m-phenyl benzyl

REFERENCES:
patent: 4782061 (1988-11-01), Kruse et al.
patent: 2005/0107396 (2005-05-01), Eijgendaal et al.
patent: 0 189 612 (1986-08-01), None
patent: 4-26683 (1992-01-01), None
patent: WO 97/36893 (1997-10-01), None
patent: WO 99/05134 (1999-02-01), None
patent: WO 00/29397 (2000-05-01), None

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