Mesoporous silica having controlled-release on-off control...

Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter

Reexamination Certificate

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C428S403000, C423S335000

Reexamination Certificate

active

06902806

ABSTRACT:
The present invention provides a hexagonal mesoporous silica comprising a photo-dimerizable organic functional group provided at the entrances of the pores thereof, and a hexagonal mesoporous silica comprising a functional substance filled in the pores thereof and a dimerized organic functional group provided at the entrances of the pores to close the entrances. These hexagonal mesoporous silicas allow a substance incorporated therein to be controllably released. The present invention also provides a method of producing the mesoporous silica, and a method using the mesoporous silica to control the release of a functional substance incorporated therein.

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Database MEDLINE Online!US National Library of Medicine (NLM), Bethesda, MD, US; Jan. 23, 2003 Mal Nawal Kishor et al: “Photocontrolled reversible release of guest molecules from coumarin-modified mesoporous silicia.” Database accession No. NLM12540896 XP002251459 *abstract* & Nature. England, vol. 421, No. 6921, p.p. 350-353, ISSN: 0028-0836.
Database BIOSIS Online! Biosciences Information Service, Philadelphia, PA, US; Apr. 16, 2003 Lai Cheng-Yu et al: . “A mesoporous silicia nanosphere-based carrier system with chemically removable CdS nanoparticle caps for stimuli-responsive controlled release of neurotransmitters and drug molecules>” Database accession No. PREV200300306683 XP002251460 *abstract* & Journal of the American Chemical Society, vol. 125, No. 15, p.p. 4451-4459, ISSN: 0002-7863.
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