Coating processes – Coating by vapor – gas – or smoke – Mixture of vapors or gases utilized
Reexamination Certificate
2007-09-18
2007-09-18
Fortuna, Ana M. (Department: 1723)
Coating processes
Coating by vapor, gas, or smoke
Mixture of vapors or gases utilized
C210S490000, C210S500100, C210S500350, C436S172000, C435S006120, C435S287200, C204S400000, C204S403060, C422S068100, C422S050000
Reexamination Certificate
active
11082325
ABSTRACT:
The present invention provides improved synthetic polymer hydrogel permeation layers for use on active electronic matrix devices for biological assays. The present invention includes methods for forming a permeation layer on an array of microelectrodes including the steps of attaching a linker to the surface of the array by treating the surface with a linker by vapor deposition and providing a polymerization solution that includes at least one monomer having a polymerizable moiety, a modified streptavidin, a surfactant or porogen, and a cross-linking agent. The surface of the array is then contacted with the polymerization solution and the polymerization solution is then polymerized on the surface of the array to form a permeation layer that is attached o the surface of the array through the linker.
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Havens John R.
Krotz Jainamma
Onofrey Thomas J.
Reese Howard R.
Smolko Daniel J.
Fortuna Ana M.
Nanogen Inc.
O'Melveny & Myers LLP
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