Mesangial cell lines as models for the study and treatment of di

Details Mesangial cell lines as models for the study and treatment of di Mesangial cell lines as models for the study and treatment of di

1995-09-01

1999-08-17

Ketter, James

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 792, 4353201, 435353, 536 231, G01N 33567

Patent

active

059392754

ABSTRACT:
An isolated and stable clone of mesangial cells which exhibit characteristics of diabetic cells when grown in normal glucose medium. The cells demonstrate an increase in glucose transport over normal mesangial cells and that provides a model for simulating diabetes in mesangial cells. Further, a stable, permanent clone of mesangial cells which underexpress GLUT1 mRNA and protein and which can be used therapeutically has been isolated.

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