Merosin fragments and uses thereof

Details Merosin fragments and uses thereof Merosin fragments and uses thereof

1995-06-02

1998-11-17

Loring, Susan A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

530350, C12P 2106, C07K 100

Patent

active

058374965

ABSTRACT:
This invention provides an isolated nucleic acid molecule encoding a subunit of a protein, the protein having an apparent molecular weight of about 800 kD, designated merosin. Also provided are isolated nucleic acid molecules which encode merosin fragments. Anti-merosin antibodies, vectors for the recombinant production of merosin, and the expression of recombinant proteins by use of a host vector system also are provided. The invention further provides the use of merosin to promote neurite growth and for certain diagnostic applications.

REFERENCES:
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