Mercaptosuccinyl glycyl-glycyl-glycine a complex thereof with Tc

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.

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424 11, 514 18, H61K 3702, C07K 508

Patent

active

048838624

ABSTRACT:
The novel compound mercaptosuccinyl glycyl-glycyl-glycine (MSG.sub.3) and a stable complex thereof with technetium-99m (Tc-99m) having utility as a renal agent. MSG.sub.3 is made by coupling glycyl-glycyl-glycine with S-acetyl-mercapto succinic anhydride.

REFERENCES:
patent: 2900375 (1959-08-01), Amiard et al.
patent: 4115374 (1978-09-01), Ryan et al.
patent: 4382081 (1983-05-01), Sundeen et al.
patent: 4709013 (1987-11-01), Nagano

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