Mercaptoacetylamide derivatives useful as inhibitors of enkephal

Details Mercaptoacetylamide derivatives useful as inhibitors of enkephal Mercaptoacetylamide derivatives useful as inhibitors of enkephal

1993-11-09

1995-07-04

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540522, A61K 3155, C07D22316, C07D48704, C07D51304, C07D49804

Patent

active

054301459

ABSTRACT:
The present invention relates to certain novel mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and of ACE.

REFERENCES:
patent: 3334091 (1967-07-01), Houlihan
patent: 3334095 (1967-08-01), Houluhan
patent: 4080449 (1978-03-01), Croisier et al.
patent: 4320057 (1982-03-01), Freed et al.
patent: 4391752 (1983-07-01), Crossley
patent: 4399136 (1983-08-01), Hassall et al.
patent: 4487929 (1984-12-01), Hassall et al.
patent: 4692438 (1987-09-01), Hassall et al.
patent: 4716232 (1987-12-01), Ternansky
patent: 4734504 (1988-03-01), Holmes
patent: 4734505 (1988-03-01), Holmes
patent: 4762924 (1988-08-01), Hassall et al.
patent: 4782149 (1988-11-01), Lawton et al.
patent: 4785093 (1988-11-01), Hassall et al.
patent: 4826980 (1989-05-01), Hassall et al.
patent: 5238932 (1993-08-01), Flynn et al.
J. Med. Chem. 1992, 35, 823-832, Timothy D. Ocain et al.
Bioorganic and Medical Chem. Letters vo. 1, 309, 1991.
Fournie-Zaluski, Marie-Claude et al., J. Med. Chem., 1992 vol. 35, pp. 2473-2481.
Fournie-Zaluski, Marie-Claude et al., J. Med. Chem., 1992 vol. 35, pp. 1259-1266.
French, John F., Jour. of Pharm and Exper. Therapeutics, vol. 268, No. 1, pp. 180-186 (1994).
W. H. Parsons et al. Biochemical and Biophysical Research Communications vol. 117, No. 1, 1993 (Nov. 30, 1983).
Burkholder, et al. Bioorganic and Medical Chem. Letters, vol. 3, No. 2, pp. 231-234, (1993).
Flynn et al., J. Med. Chem. 1993, 36 2420-2423.

Affiliated with

Also associated with

Rating

Mercaptoacetylamide derivatives useful as inhibitors of enkephal does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mercaptoacetylamide derivatives useful as inhibitors of enkephal, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mercaptoacetylamide derivatives useful as inhibitors of enkephal will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-761173