Mepyramine theophylline acetate

Details Mepyramine theophylline acetate Mepyramine theophylline acetate

1974-10-16

1976-06-08

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424253, C07D47308

Patent

active

039622436

ABSTRACT:
The 7-theophylline acetic acid salt of mepyramine possesses bronchial spasmolytic, antiarrhythmic, cerebral oxidation inhibitor and platelet aggregation inhibitor properties. It is prepared by slowly adding a solution of mepyramine to a suspension of 7-theophylline acetic acid in the same solvent to effect the salt-forming reaction. It can be incorporated in various pharmaceutical unit dosage forms.

REFERENCES:
patent: 2534235 (1950-12-01), Cusic
patent: 2942000 (1960-06-01), Mizier
patent: 3098854 (1963-07-01), Klosa
patent: 3190920 (1965-06-01), Spickett et al.

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