Meningococcal vaccines formulated with interleukin-12

Details Meningococcal vaccines formulated with interleukin-12 Meningococcal vaccines formulated with interleukin-12

2005-01-11

2005-01-11

Graser, Jennifer E. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S195110, C424S184100, C424S193100, C424S198100, C424S085200, C424S236100, C424S238100, C514S002600, C514S008100, C514S012200, C514S054000, C514S885000

Reexamination Certificate

active

06841160

ABSTRACT:
This invention pertains to vaccine compositions comprising a mixture of antigen, such as pneumococcal or meningococcal antigen, and interleukin IL-12, which may be adsorbed onto a mineral in suspension. The pneumococcal or meningococcal antigen may be conjugated to a carrier molecule. These vaccine compositions modulate the protective immune response to the antigen.

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Metzger et al. Eur. J. Immunol. 1997. 27:1958-1965.*
Miller et al. J. Immunol. 1995. 155 (10):4817-4825.

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