Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1998-02-11
1999-10-19
Lee, Howard C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
4241941, 42419711, 4242501, 514 42, 514 54, 5361231, 530395, 530403, C07H 506, C08B 3700, C07K 100
Patent
active
059691301
ABSTRACT:
The invention relates to chemically-modified group B polysaccharides of Neisseria meningitidis. The invention also provides vaccines in which the respective modified polysaccharides are conjugated to a protein carrier, and the like. More specifically, the present invention provides novel group B meningococcal unsaturated N-acyl derivative polysaccharides, novel conjugates of the group B meningococcal unsaturated N-acyl derivative polysaccharides, pharmaceutical compositions comprising conjugate molecules of group B meningococcal unsaturated N-acyl derivative polysaccharide fragments covalently bound to proteins, and the use of these compositions as vaccines.
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Jennings Harold J.
Lussier Michele
Michon Francis
Pon Robert
Lee Howard C.
National Research Council of Cananda
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