Memory enhancing protein

Details Memory enhancing protein Memory enhancing protein

2011-04-19

2011-04-19

Pak, Michael (Department: 1646)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

Reexamination Certificate

active

07928070

ABSTRACT:
The present invention provides methods and compositions for enhancing memory in animals, including humans by the administration of an effective amount of an atypical form of protein kinase C such as protein kinase M zeta (PKMζ) or protein kinase C iota/lambda.

REFERENCES:
patent: 6268398 (2001-07-01), Ghosh et al.
patent: 2004/0247584 (2004-12-01), Sacktor
patent: 2005/0064501 (2005-03-01), Lang et al.
patent: 2005/0070565 (2005-03-01), Arnsten et al.
Thiam et al. (1999) FEBS Letter 459: 285-290.
Barad et al. Society for Neuroscience Abstracts 24(1-2): p. 328, abstract No. 131.14 (1998).
Osten, P. et al., “Protein Synthesis-Dependent Formation of Protein Kinase Mζ in Long-Term Potentiation”,Journal of Neuroscience 16(8): 2444-2451 (1996).
Hrabetova, S. et al., “Bidirectional Regulation of Protein Kinase Mζ in the Maintenance of Long-Term Potentiation and Long-Term Depression”,Journal of Neuroscience 16(17): 5324-5333 (1996).
Bareggi, R. et al., “Selective Distribution of Multiple Protein Kinase C Isoforms In Mouse Cerebellar cortex”,Biol. Cell 87: 655-63 (1996).
Barad, M. et al., “Mice Overexpressing A Constitutively Active PKMζ Derived Transgene in Brain under CAMKII Promoter Control Show Defects' In Memory and Increased Incidence of Neurofibromas”,Abstracts of the Society for Neuroscience 24(1-2): 328 (1998), XP-002967921.
Drier, E. A. et al., “Enhancement of Memory inDrosophilaVia Induction of a Mouse PKC Isoform, MPKM-&#43B”,Abstracts of the Society for Neuroscience 26(1-2): 94 (2000), XP-002967918.
Ling, D. S. F. et al., “Protein Kinase Mζ Is Necessary and Sufficient for LTP Maintenance”,Nature Neuroscience 5(4): 295-296 (2002), XP-002310112.

Affiliated with

Also associated with

Rating

Memory enhancing protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Memory enhancing protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Memory enhancing protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2741689