Membrane structure coated with low pI protein or carbohydrate an

Details Membrane structure coated with low pI protein or carbohydrate an Membrane structure coated with low pI protein or carbohydrate an

1987-09-18

1989-05-09

Marantz, Sidney

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

21050038, 427244, 427245, 4283155, 4283157, 4283159, 435 36, 436529, 436533, 436534, 436807, 436824, G01N 33546, G01N 33569

Patent

active

048289809

ABSTRACT:
A membrane structure useful in filtration and diagnostic tests includes a microporous membrane formed from a biologically inert material, such as a polyamide, and has a coating comprising one or more water-soluble proteins or carbohydrates. None of the proteins and carbohydrates in the coating has a pI greater than about 5. The membrane structure is prepared by contacting the microporous membrane with the appropriate protein or carbohydrate in an amount sufficient to provide a coating over the entire membrane surface without substantially diminishing the porosity of the membrane. The membrane structure is useful in various diagnostic test procedures, such as agglutination assays.

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Meth. in Enzymology, vol. XXV, 1972, pp. 531-536, Klapper, M. H. and Klotz, I. M. "Acylation with Dicarboxylic Acid Anhydrides".
Johnson et al, Gene. Anal. Techn. 1 (1984) pp. 3-8.

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