Membrane-strip reagent serodiagnostic apparatus and method

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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422 56, 422 57, 422 58, 435 794, 435288, 435299, 435300, 435301, 435311, 435805, 435810, 436177, 436178, 436518, 436528, 436530, 436531, 436535, 436808, 436810, 436811, 436813, 436820, G01N 33538, G01N 33545, G01N 33549, G01N 33569

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active

050305557

ABSTRACT:
For the serodiagnosis of a fluid sample, it is particularly advantageous to use a device comprising (A) a supported, porous membrane wherein a first immunoreagent is bound so as to be capable of binding a foreign analyte and forming a complex when the foreign analyte is brought into contact therewith; and (B) a matrix which presents a first surface and an opposing second surface and which contains a second, labeled immunoreagent that is capable of binding the foreign analyte to form a labeled complex when the foreign analyte is sandwiched between the first immunoreagent and the second immunoreagent. In such a device, the first surface of the matrix is adjacent to a surface of the membrane, (ii) the matrix is wettable by or soluble in an aqueous fluid, and (iii) the second immunoreagent is mobilized when the matrix is wetted.

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