Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-01-19
1989-04-18
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546236, 546240, C07D21108, C07D21122, A61K 31445
Patent
active
048227781
ABSTRACT:
Compounds of the formula (I) ##STR1## optically active isomers thereof, and/or pharmaceutically acceptable acid addition salts thereof are disclosed, wherein R.sup.1 is selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, n-butyl, 2-hydroxyethyl, 3-hydroxypropyl and 4-hydroxybutyl, and wherein R is selected from the group consisting of ##STR2## in which R.sup.2, R.sup.3 R.sup.4 and R.sup.5 are the same or different and are each independently selected from the group consisting of hydrogen and methyl. Pharmaceutical preparations employing such compounds and method of using such compounds are also disclosed.
REFERENCES:
patent: 3634437 (1972-01-01), Todd
patent: 3709892 (1973-01-01), Leeming et al.
patent: 4225608 (1980-09-01), Uhl et al.
patent: 4243807 (1981-01-01), Friebe et al.
Aberg Gunnar A. K.
af Ekenstam Bo T.
Aberg Gunnar
Rotman Alan L.
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