Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1988-05-25
1992-10-06
Rosen, Sam
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
530413, 530820, 530822, C12N 950
Patent
active
051531291
ABSTRACT:
An immunogenic composition for use as a vaccine against malaria. It comprises an enzymatically active protease with a molecular weight of 76.000 daltons, characterized by its capacity to react with protective antibodies originating from monkeys resistant to human malaria parasites, particularly to Plasmodium falciparum.
REFERENCES:
patent: 5032397 (1991-07-01), Dubois et al.
Schrevel et al.-Chem. Abst., vol. 102 (1985) p. 74,557h.
Vander et al.-Chem. Abst., vol. 104 (1986) p. 211,149y.
Perrin et al.-Immunological Reviews, vol. 61 (1982) pp. 245 to 269.
Breton Catherine
Pereira da Silva Luiz
Institut Pasteur
Rosen Sam
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