Membrane protein having proteolytic activity obtainable from pla

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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530413, 530820, 530822, C12N 950

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active

051531291

ABSTRACT:
An immunogenic composition for use as a vaccine against malaria. It comprises an enzymatically active protease with a molecular weight of 76.000 daltons, characterized by its capacity to react with protective antibodies originating from monkeys resistant to human malaria parasites, particularly to Plasmodium falciparum.

REFERENCES:
patent: 5032397 (1991-07-01), Dubois et al.
Schrevel et al.-Chem. Abst., vol. 102 (1985) p. 74,557h.
Vander et al.-Chem. Abst., vol. 104 (1986) p. 211,149y.
Perrin et al.-Immunological Reviews, vol. 61 (1982) pp. 245 to 269.

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