Membrane, process and system for isolating virus from solution

Details Membrane, process and system for isolating virus from solution Membrane, process and system for isolating virus from solution

1990-12-05

1992-03-17

Sever, Frank

Plastic and nonmetallic article shaping or treating: processes

Pore forming in situ

Composite article making

264DIG48, 264DIG62, B01D 6114, B01D 6700

Patent

active

050966375

ABSTRACT:
A composite membrane and process utilizing the membrane which is capable of selectively removing particles such as viral particles from a solution such as a protein solution is provided. The membrane comprises a porous membrane substrate, a surface skin having ultrafiltration separation properties and an intermediate porous zone between the substrate and the skin which intermediate zone has an average pore size smaller than that of the substrate. The intermediate zone is free of voids which break the skin and which directly fluid communicate with the substrate. The composite is capable of a log reduction value of at least 3 (99.9% removal) of particles selectively from solution.

REFERENCES:
patent: 4689150 (1987-08-01), Abe et al.

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