Membrane, process and system for isolating virus from solution

Details Membrane, process and system for isolating virus from solution Membrane, process and system for isolating virus from solution

1990-05-10

1991-05-21

Sever, Frank

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210654, 21050036, 21050042, B01D 1614

Patent

active

050172921

ABSTRACT:
A composite membrane and process utilizing the membrane which is capable of selectively removing particles such as viral particles from a solution such as a protein solution is provided. The membrane comprises a porous membrane substrate, a surface skin having ultrafiltration separation properties and an intermediate porous zone between the substrate and the skin which intermediate zone has an average pore size smaller than that of the substrate. The intermediate zone is free of voids which break the skin and which directly fluid communicate with the substrate. The composite is capable of a log reduction value of at least 3 (99.9% removal) of particles selectively from solution.

REFERENCES:
patent: 4473474 (1984-09-01), Ostreicher et al.
patent: 4673504 (1987-06-01), Ostreicher et al.
patent: 4708803 (1987-11-01), Ostreicher et al.

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