Membrane plasmapheresis apparatus and process which utilize a fl

Details Membrane plasmapheresis apparatus and process which utilize a fl Membrane plasmapheresis apparatus and process which utilize a fl

1986-12-15

1988-05-24

Fisher, Richard V.

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210109, 210137, 21032165, 21032189, 210651, 210741, B01D 1300

Patent

active

047464364

ABSTRACT:
A membrane plasmapheresis system introduces a flow of whole blood subject to a predetermined inlet pressure into a fluid path across a membrane which is suited for filtering the plasma from the whole blood and across which a predetermined pressure drop occurs. The plasma-poor blood is conducted from the membrane subject to a determinable plasma-poor blood pressure. Likewise, plasma filtrate is conducted from the membrane subject to a determinable plasma-filtrate pressure. The conduction of plasma filtrate is metered in response to the existent plasma-poor blood pressure to achieve and thereafter maintain substantial equilibrium between the plasma-poor blood pressure and the plasma filtrate pressure. A substantially constant transmembrane pressure can thereby be maintained at a level below which hemolysis occurs.

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