Membrane-permeant second messengers

Details Membrane-permeant second messengers Membrane-permeant second messengers

1993-04-09

1997-12-02

Rories, Charles C. P.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

514 45, 514 47, 514 48, 435 721, 4352402, 536 267, 536 2671, 536 2672, 536 273, 536117, A61K 3170, C07H 19167, C07H 1920, C12N 500

Patent

active

056935218

ABSTRACT:
Acyloxyalkyl esters of phosphate-containing second messengers which are capable of permeating cell membranes. Once inside the cell, the ester derivatives undergo enzymatic conversion to the biologically active form of the second messenger. Acyloxyalkyl esters of second messengers, such as cAMP, cGMP, inositol triphosphate and inositol tetraphosphate are disclosed.

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