Membrane Na.sup.+ channel protein and related therapeutic compou

Details Membrane Na.sup.+ channel protein and related therapeutic compou Membrane Na.sup.+ channel protein and related therapeutic compou

1987-08-14

1990-08-21

Richman, Barry S.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436 63, 436531, 530350, 530395, 530400, 530417, 530813, G01N 3353, C07K 320

Patent

active

049505912

ABSTRACT:
A channel protein has a Na.sup.+ /K.sup.+ selectivity of approximately 100 and capable of affecting Na.sup.+ membrane transport. Amiloride derivatives, and amiloride gel materials incorporating such derivatives, are useful in treating membrane transport, cellular volume and cellular pressure disorders and in isolating the channel protein. The channel protein is used in diagnostic assays and screening assays.

REFERENCES:
patent: 4362737 (1982-12-01), Shafer et al.
Hamilton, Kirk L., et al., Am. J. Physiol., vol. 249, pp. C200-C207 (1985).
Hamilton, Kirk L., et al., Fed. Proc., vol. 45, pp. 2713-2717 (1986).
Palmer, Lawrence G., J. Membrane Biol., vol. 96, pp. 97-106 (1987).
Sariban-Sohraby, et al., Nature, vol. 308, pp. 80-82 (1984).

Affiliated with

Also associated with

Rating

Membrane Na.sup.+ channel protein and related therapeutic compou does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Membrane Na.sup.+ channel protein and related therapeutic compou, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Membrane Na.sup.+ channel protein and related therapeutic compou will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1677118