Membrane expression of heterologous genes

Details Membrane expression of heterologous genes Membrane expression of heterologous genes

1991-11-15

1994-10-18

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 671, 4351721, 4351723, 4352523, 4353201, 536 231, 536 237, 536 243, C12N 121, C12N 1530, C12N 1570, C12N 1574

Patent

active

053567978

ABSTRACT:
The invention relates to nucleic acid segments useful in the construction of expression vectors for expression of heterologous polypeptides directed to particular areas of the host cell. Selected constructs direct production of polypeptides to the outer membrane surface of the cell. Other constructs direct expression of heterologous polypeptides to the inner membrane/periplasm of the host cell. Transformed host cells are potentially useful for the production of vaccines or immunogens elicited in response to antigens expressed on the outer membranes of the host cells.

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