Membrane architectures for ion-channel switch-based...

Details Membrane architectures for ion-channel switch-based... Membrane architectures for ion-channel switch-based...

2005-03-04

2008-10-28

Monshipouri, Maryam (Department: 1656)

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Analysis, diagnosis, measuring, or testing product

C427S002110, C216S066000

Reexamination Certificate

active

07442403

ABSTRACT:
The present invention is directed to a process of forming a bilayer lipid membrane structure by depositing an organic layer having a defined surface area onto an electrically conductive substrate, removing portions of said organic layer upon said electrically conductive substrate whereby selected portions of said organic layer are removed to form defined voids within said defined surface area of said organic layer and defined islands of organic layer upon said electrically conductive substrate, and, depositing a bilayer lipid membrane over the defined voids and defined islands of organic layer upon said substrate whereby aqueous reservoirs are formed between said electrically conductive substrate and said bilayer lipid membrane, said bilayer lipid membrane characterized as spanning across the defined voids between said defined islands. A lipid membrane structure is also described together with an array of such lipid membrane structure.

REFERENCES:
patent: 7132122 (2006-11-01), Parikh et al.

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