Membrane anchor fusion polypeptides

Details Membrane anchor fusion polypeptides Membrane anchor fusion polypeptides

1987-08-06

1992-04-28

Moskowitz, Margaret

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530359, 530405, 530409, 530806, 530807, 530808, 435 697, C07K 1300

Patent

active

051091135

ABSTRACT:
Novel fusions of a phospholipid anchor domain and a polypeptide heterologous to the anchor domain donor polypeptide are provided for industrial use. Therapeutic administration of the fusions enables the targeting of biological activity to cell membrane surfaces.

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Medof et al., J. Exp. Med. 160:1558-1578 (1984).
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Fearon, D. T., P.N.A.S. 76(11):5867-5871 (1979).
Ross et al., J. Immunol. 129(5):2051-2060 (1982).
Medicus et al., Eur. J. Immunol. 13:465-470 (1983).

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